Antipsychotic deflates the brain : Nature News: "A leading antipsychotic drug temporarily reduces the size of a brain region that controls movement and coordination, causing distressing side effects such as shaking, drooling and restless leg syndrome.
Just two hours after injection with haloperidol, an antipsychotic commonly prescribed to treat schizophrenia, healthy volunteers experienced impaired motor abilities that coincided with diminished grey-matter volume in the striatum1 — a brain region that mediates movement.
'We've seen changes in the brain before, but to see significant remodelling of the striatum within a couple of hours is staggering,' says Clare Parish at the Howard Florey Institute for brain research in Melbourne, Australia, who was not involved in the study. 'Our viewpoint was that only chemical changes would happen in such a short time.'"
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